Pascal Siakam scored 23 points and Bennedict Mathurin 19 for the Pacers, who had their six-game winning streak halted. Myles Turned added 17 points.
The Cavaliers led 82-77 in the third quarter before going on a 10-0 run that included 3-pointers by Max Strus, Georges Niang and Mobley. Cleveland led 100-89 after three periods.
Indiana cut its deficit to 111-106, but could get no closer.
With Indiana trailing 120-111, Mathurin lost his cool and was ejected after drawing his second technical with 3:58 left. Mitchell sank both technical free throws and Mobley hit one of two free throws.
The Pacers had ended the host Cavaliers’ 12-game winning streak with a 108-93 victory on Sunday night.
Indiana played without All-Star point guard Tyrese Haliburton, who was sidelined with left groin strain.
Takeaways
Cavaliers: Cleveland was able to bounce back from their first loss since Dec. 8 with a 49-37 rebounding edge. The Cavaliers shut down Siakam in the second half, limiting him to two points and five shots.
Pacers: Indiana missed Haliburton, and his replacement, Ben Sheppard, had just two assists and shot 1 for 6.
Key moment
After the Pacers closed the deficit to 115-109, Garland sank a 27-foot, 3-pointer to put Cleveland ahead 118-109 with 4:48 left.
Key stat
The Cavaliers sank 26 of 31 free throws. That was nine more free throws than the Pacers (17 of 22). Both teams shot 48% from the field.
Up next
The Cavaliers are at Oklahoma City on Thursday in a matchup of the East and West conference leaders. The Pacers are at Detroit on Thursday.
Credit: AP
Credit: AP
Credit: AP
Credit: AP
Credit: AP
Credit: AP
Credit: AP
Credit: AP